Basic Info.
Product Description
Product Introduction:
Product name | Chloramphenicol |
Others name | [theta-(theta,theta)]-;[R-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]ethanamide;2,2-dichloro-n-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-acetamid;2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-,[R-(R*,R*)]-Acetamide;2,2-dichloro-n-[2-hydroxy-1-(Chemicalbookhydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamid;Acetamide,2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl);Acetamide,2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-,[R-(R*,R*)]-;Acetamide,2,2-dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl]-,D-threo-(-)- |
Apperance | White powder |
Purity | 99% |
CAS No. | 56-75-7 |
Shelf time | 2 years,keep away sunlight, keep dry |
Chloramphenicol is a broad spectrum antibiotic which inhibits translation on the 50S
ribosomal subunit at the peptidyltransferase step. It is usually bacteristatic and effective
against a wide range of gram-positive and gram-negative organisms. Chloramphenicol
exhibits anti-rickettsial activity and is also active against chlamydias of the
psittacosis-lymphogranuloma group. Obtained from cultures of the soil bacterium Streptomyces
venuzuelae isolated from the moon snail, Lunatia heros and produced synthetically. Useful
for the selection of the bacterial CAT gene.
Functions:
Chloramphenicol is unusual nitroaromatic metabolite produced by Streptomyces venezuelae,
first published in 1947. Chloramphenicol is a broad spectrum antibiotic with good activity
against Gram negative and anaerobic bacteria. Although restricted to ocular use, antibiotic
resistance to other classes has refocused attention on this class. Chloramphenicol acts by
binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Chloramphenicol
has been extensively studied with over 35,000 literature citations.
Packing:
1kg/bag, 25kgs/drum (Two plastic-bags inside and Paper-drums or per customer's requirements.)
Storage:
Store in tight, light-resistant containers, avoid exposure to direct sunlight, moisture and excessive heat.
Shelf Life: 24 months.